mavorixafor will enhance the amount or impact of codeine by influencing hepatic enzyme CYP2D6 metabolism. Contraindicated. Mavorixafor (a robust CYP2D6 inhibitor) is contraindicated with medications which might be remarkably depending on CYP2D6 for clearance.
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artemether/lumefantrine will enhance the level or effect of codeine by impacting hepatic enzyme CYP2D6 metabolism. Use Warning/Watch.
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desipramine decreases outcomes of codeine by influencing hepatic enzyme CYP2D6 metabolism. Use Warning/Keep an eye on. Stops conversion of codeine to its Energetic metabolite morphine.
The codeine may perhaps boost frequency of seizures in clients with seizure Conditions, and should enhance chance of seizures developing in other scientific configurations connected to more info seizures; keep track of patients having a history of seizure Issues for worsened seizure Management through therapy
The above mentioned facts is supplied for normal informational website and educational needs only. Specific options could differ and formulary facts adjustments. Call the applicable plan company for probably click here the most latest information.
codeine and daridorexant each increase sedation. Modify Therapy/Keep track of Intently. Coadministration will increase chance of CNS melancholy, which can result in additive impairment of psychomotor functionality and result in daytime impairment.
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